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Pharmaceutical intermediates

Anti-tumor drugs

Name

Key intermediate

CAS NO
Axitinib

3,6-diiodo(1H)indazole

Methyl 2-mercaptobenzoate

319472-78-1

4892-02-8

Crizotinib

4-Iodo-1H-pyrazole

(R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-2-nitropyridine

4-(4-Bromopyrazol-1-yl)piperidine-1-carboxylic acid tert-butyl ester

(R)-5-bromo-3-(1-

3469-69-0

877397-70-1

877399-50-3

877399-00-3

Lapatinib

2-(Methylsulfonyl)-ethanamine hydrochloride

N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine

3-Chloro-4-(3-fluorobenzyloxy)aniline

104458-24-4

231278-20-9

202197-26-0

Pazopanib

3-Methyl-6-nitro-1H-Indazole

2,3-dimethyl-6-nitro-2H-indazole

2,3-dimethyl-2H-indazol-6-amine

2,4-Dichloropyrimidine

3-Amino-6-methylbenzenesulfonam

6494-19-5

444731-73-1

444731-72-0

3934-20-1

6973-09-7

Regorafenib

3-Fluoro-4-Nitrophenol

3-Fluoro-4-aminophenol

394-41-2

399-95-1

Afatinib

trans 4-Dimethylaminocrotonic acid hydrochloride

848133-35-7

Gefitinib

4-(3-chloropropyl)-morpholin

7357-67-7

Anti-inflammatory drugs

Name

Key intermediate

CAS NO
Tofacitinib

1-benzyl-4-methylpiperidin-3-ol 4-methylbenzenesulfonate

(3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine hydrochloride

2,4-Dichloro-1H-pyrrolo[2,3-d]pyrimidine

3-bis(4-

493040-20-3

477600-70-7

90213-66-4

477600-71-8

Formoterol

2-Bromo-4'-Benzyloxy-3'-nitroacetophenone

(1R,2S)-1-Amino-2-indanol

43229-01-2

136030-00-7

Umeclidiniu

Phenyl(piperidin-4-yl)methanone

37586-22-4

Hypoglycemic agents

Name

Key intermediate

CAS NO
Alogliptin

(R)-3-Boc-aminopiperidine

309956-78-3

Anagliptin

2-Methylpyrazolo[1,5-a]pyriMidine-6-carboxylic acid

2-Methylpyrazolo[1,5-a]pyrimidine-6-carboxamide

1,2-Diamino-2-methylpropane

739364-95-5

338953-49-4

811-93-8

Dapagliflozin

5-Bromo-2-chloro-4’-ethoxydiphenylmethane

4-Iodo-1-chloro-2-(4-ethoxybenzyl)benzene

(5-bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone

461432-23-5

1103738-29-9

461432-22-4

Vildagliptin

3-Amino-1-adamantanol

(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile

L-Prolinamide

702-82-9

207557-35-5

7531-52-4

Canagliflozin

2-(4-fluorophenyl)thiophene

(5-(4-fluorophenyl)thiophen-2-yl)(5-iodo-2-methylphenyl)methanone

2-(4-fluorophenyl)-5-(5-iodo-2-methylbenzyl)thiophene

(5-bromo-2-methylph

58861-48-6

1071929-08-2

898566-17-1

1132832-75-7

1030825-20-7

Anticoagulants drugs

Name

Key intermediate

CAS NO
Dabigatran

N-(4-Cyanophenyl)glycine

4-(Methylamino)-3-nitrobenzoic Acid

3-(Pyridin-2-ylamino)propanoate

Ethyl N-[3-amino-4-(methylamino)benzoyl]-N-pyridin-2-yl-beta-alaninate

42288-26-6

41263-74-5

103041-38-9

212322-56-0

Ticagrelor

4,6-dichloro-5-nitro-2-(propylsulfanyl)pyrimidine

(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine

(1R,2R)-2-(3,4-difluorophenyl) cyclopropanamine(S)-(carboxylato(phenyl) methyl)h

145783-14-8

220352-38-5

376608-71-8

Antiepileptics drugs

Name

Key intermediate

CAS NO
Retigabine (ezogabine)

2-Amino-5-[(4-fluorobenzyl)amino]-1-nitrobenzene

4-(4-Fluorobenzylamino)-1,2-phenylenediamine

150812-21-8

491871-67-1

Anti-HIV drugs

Name

Key intermediate

CAS NO
Abacavir

(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide

(1S,4R)-4-(2-amino-6-chloro-9H-purin-9-yl)-2-Cyclopentene-1- methano

171887-03-9

136522-33-3

Etravirine

(4-Cyanophenyl)guanidine

4-Aminobenzonitrile

5637-42-3

873-74-5

Ritonavir

154212-59-6

154212-61-0

144164-11-4

154212-59-6

154212-61-0

144164-11-4

Atazanavir

4-(2-Pyridinyl)- benzaldehyde

N-(Methoxycarbonyl)-L-tert-leucine

Tert-Butyl[(1S)-1-(2R)-Oxiranyl-2-Phenylethyl]carbamate

2-[[4-(2-Pyridinyl)phenyl]methylene]- hydrazin

127406-56-8

162537-11-3

98760-08-8

198904-84-6

198904-86-8

Aliskiren

5-Bromo 2-methoxy phenol

37942-01-1

Antihypertensives drugs

Name

Key intermediate

CAS NO
Aliskiren

5-Bromo 2-methoxy phenol

37942-01-1

Custom Products

Code

Name

CAS NO

112 Chloro [1,1-biphenyl] 2,5-diol

117-71-5

113 3-amino-2-methoxy-dibenzofuran

5834-17-3

120 2-methoxy - dibenzofuran 20357-70-4
394 2- hydroxydibenzofuran 86-77-1
396 3-nitro-2-methoxy-dibenzofuran 2672-81-3
392 3-hydroxy -N- (2- methoxy-3-dibenzofuran-yl) -2-naphthalene-carboxamide 96460-88-7
810 3-phenoxy-propionic acid ethyl ester 22409-91-2
368 Heptachloropropane 3849-33-0
246 Dibenzyl diphosphite of tetraethyl 4546-4-7
372 2-nitropropane 79-46-9
373 2,3-dimethyl-2,3-dinitro-butane 3964-18-9
202 4,4-diiodo-biphenyl 3001-15-8
1016 2,4 Nitrodiphenylamine

961-68-2

1024 Cinnamic acid isopropyl ester 3001-15-8
325 Dichloro glyoxime 2038-44-0
1037 Acetoacetate (2-methoxy) ethyl 22502-03-0
1074 D-3-bromo-camphor-8-sulfonic acid ammonium salt 22502-03-0
111 Arecoline hydrobromide hydrochloride 300-08-3
201 4- iodobiphenyl 1591-31-7
375 2-methyl-4,6-dichloro-5-aminopyrimidine 39906-04-2
601 Diethyl oxaloacetate sodium salt 40876-98-0
990 O Nitrodiphenylamine 119-75-5
925 Azomethine -H- monosodium salt monohydrate 206752-32-1
1035 4-hydroxyisophthalic acid 636-46-4
6-Chloro-indol-2-one 56341-37-8
2- -aminoindan 2975-41-9
1- Bromocarbazole 16807-11-7
N- methyl trifluoroacetamide 815-06-5
2,8-dibromo dibenzofuran 10016-52-1
2-bromo-1- (2,2-dimethyl -4H-1,3- benzodioxin-6-yl) ethanone 102293-80-1
N, N- diethyl ethyl acrylate 13894-28-5
3'-nitro-4'-benzyloxy-2-bromoacetophenone 43229-01-2
600 6-hydroxy-1-naphthoic acid 2437-17-4
Between 4-methoxy-phthalate 2206-43-1
2-nitropropane 79-46-9
D-3-bromo-camphor-8-sulfonic acid ammonium salt D-3-bromo-camphor-8-sulfonic acid ammonium salt
dioctyl 3,4,5,6-tetrabromophthalate

26040-751-7

Benzonitrile, 3-ethoxy-4-methoxy-

60758-86-3

1-Bromo-3-ethoxy-4-methoxybenzene

52849-52-2

4-Bromoveratrole

2859-78-1

Cyclen

294-90-6

Amisulpride

71675-85-9

Valproic acid

99-66-1

Cyclobutanecarboxylic acid

3721-95-7

DL-Mandelic acid

90-64-2;611-72-3

45 Records
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