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Pharmaceutical intermediates

Name

Key intermediate

CAS NO
Axitinib

3,6-diiodo(1H)indazole

Methyl 2-mercaptobenzoate

319472-78-1

4892-02-8

Crizotinib

4-Iodo-1H-pyrazole

(R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-2-nitropyridine

4-(4-Bromopyrazol-1-yl)piperidine-1-carboxylic acid tert-butyl ester

(R)-5-bromo-3-(1-

3469-69-0

877397-70-1

877399-50-3

877399-00-3

Lapatinib

2-(Methylsulfonyl)-ethanamine hydrochloride

N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine

3-Chloro-4-(3-fluorobenzyloxy)aniline

104458-24-4

231278-20-9

202197-26-0

Pazopanib

3-Methyl-6-nitro-1H-Indazole

2,3-dimethyl-6-nitro-2H-indazole

2,3-dimethyl-2H-indazol-6-amine

2,4-Dichloropyrimidine

3-Amino-6-methylbenzenesulfonam

6494-19-5

444731-73-1

444731-72-0

3934-20-1

6973-09-7

Regorafenib

3-Fluoro-4-Nitrophenol

3-Fluoro-4-aminophenol

394-41-2

399-95-1

Afatinib

trans 4-Dimethylaminocrotonic acid hydrochloride

848133-35-7

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